Director, Breast and Gynecological Cancer Surveillance, Surveillance and Health Services Research, American Cancer Society, Atlanta, GAAssistant Professor of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GAVice President, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.Director, Breast and Gynecological Cancer Surveillance, Surveillance and Health Services Research, American Cancer Society, Atlanta, GAAssistant Professor of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GAVice President, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.Use the link below to share a full-text version of this article with your friends and colleagues.

Rarissimes sont les hommes, comme Poincaré et Einstein, aptes à créer ou à manier les instruments logiques, les prodigieux appareils d'abréviations qui permettent de refouler, de contraindre l'infinie diversité des faits (Valéry, Entret. Name must be less than 100 characters

Overall, approximately 20% of patients with cancer in the United States are diagnosed with a rare cancer. A sample chosen randomly is meant to be an unbiased representation of the total population. The US Orphan Drug Act of 1983 defined rare diseases as those affecting less than 200,000 people in the United States.All cancers were defined using the list of cancers produced by the RARECARE study group.Incidence rates and case distributions by sex, race/ethnicity, age, and stage at diagnosis were obtained using North American Association of Central Cancer Registries (NAACCR) data from 47 states and the District of Columbia, representing 96.7% of the US population.Incidence rates and relative survival were calculated using the NCI's SEER*Stat software (version 8.3.2).We identified 181 rare cancers with overall incidence rates of fewer than 6 cases per 100,000 per year during 2009 through 2013 (Table Variations in the percentages of rare cancers by sex, race/ethnicity, and age at diagnosis are shown in Figure Distribution of Rare and Common Cancers, 2009 Through 2013, United States.NH indicates non‐Hispanic. © Rare cancers present unique challenges for clinicians and their patients. 3 In 2010, Greenlee et al described the US burden of rare cancers according to the National Cancer Institute's definition as those cancers with fewer than 15 cases per 100,000 people per year. This download provides the Realtek* High Definition Audio Driver for the 3.5mm audio jack on the Intel® NUC Kits NUC8i7HxKx. More than two‐thirds (71%) of cancers occurring in children and adolescents are rare cancers compared with less than 20% of cancers diagnosed in patients aged 65 years and older. Among solid tumors, 59% of rare cancers are diagnosed at regional or distant stages compared with 45% of common cancers.


2011 Nov;47(17):2493-511. doi: 10.1016/j.ejca.2011.08.008. Elsevier Science Epub 2017 Jul 4.Gatta G, Capocaccia R, Trama A, Martínez-García C; RARECARE Working Group.Adv Exp Med Biol. Gatta G, van der Zwan JM, Casali PG, Siesling S, Dei Tos AP, Kunkler I, Otter R, Licitra L, Mallone S, Tavilla A, Trama A, Capocaccia R; RARECARE working group.Eur J Cancer. The RARECARE group conducted a sensitivity analysis and concluded that the vast majority of NOS cases in Europe were due to genuine difficulties in assigning more specific diagnoses.Collectively, rare cancers contribute to a substantial portion of the cancer burden in the United States.

− Très rare, qui n'existe qu'en très peu d'exemplaires ou en très petite quantité.

Copyright © 2014 The Authors.




Screening of rare cancer sites is generally impractical because of the extremely large numbers of patients that would need to be screened to prevent one death.There are several limitations in this analysis of rare cancers.

It may be more difficult to diagnose and register rare cancers than common cancers. avec F. Lefèvre, 1926, p. 141). Purpose. Five‐Year Relative Survival for Rare and Common Cancers by Age at Diagnosis (Years), 2006 Through 2012, United States.Source: Surveillance, Epidemiology, and End Results (SEER) Program, 18 SEER Registries, National Cancer Institute, 2016.The proportion of late (regional/distant) stage diagnoses and the 1‐year and 5‐year relative survival rates for select rare cancers are provided in Table In this report, we provide an overview of the burden of rare cancers in the United States. Of course, some rare histologic subtypes of more common cancer sites, such as rare subtypes of adenocarcinoma of the breast, are detectable through current screening modalities.


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